Infertility help for couples having difficulty conceiving. The Fertility Center - Michigan Infertility Specialists. Michigan Reproductive & IVF Center.
  1. Infertility Information

Sample IVF Cycle

Please note that your In Vitro Fertilization (IVF) cycle may vary depending on your individual situation and determined protocol.

There are three main calendars we use at The Fertility Center. The first is where Lupron is started on day 21 of your pre-cycle month called "Long Lupron Protocol" . The second protocol is called the "Lupron Flare Protocol" or the "Microdose Lupron Protocol". The third is the "Cetrotide/Ganirelix Protocol".

Long Lupron Protocol

Pre-procedure month

day 1

menses start

day 2

 

day 3

 

day 4

 

day 5

 

day 6

 

day 7

 

day 8

 

day 9

 

day 10

 

day 11

 

day 12

 

day 13

 

day 14

 

day 15

 

day 16

 

day 17

 

day 18

 

day 19

 

day 20

 

day 21

start Lupron

day 22

Lupron

day 23

Lupron

day 24

Lupron

day 25

Lupron

day 26

Lupron

day 27

Lupron

day 28

Lupron

day 29

Lupron

day 30

Lupron

day 31

Lupron
menses start

day 32

Lupron
ultrasound

     

 

Procedure month

day 1

FSH, hMG and Lupron

day 2

FSH, hMG and Lupron

day 3

FSH and Lupron

day 4

FSH and Lupron
ultrasound estradiol

day 5

FSH and Lupron

day 6

FSH and Lupron

day 7

FSH and Lupron

day 8

FSH and Lupron
ultrasound estradiol

day 9

FSH and Lupron

day 10

FSH and Lupron
ultrasound estradiol

day 11

FSH and Lupron

day 12

FSH and Lupron
ultrasound estradiol

day 13

HCG trigger shot

day 14

no meds

day 15

Egg retreival progest., estrace

day 16

progest., estrace

day 17

embryo transfer progest., estrace

day 18

progest., estrace

day 19

progest., estrace

day 20

progest., estrace

day 21

progest., estrace

day 22

progest., estrace

day 23

progest., estrace

day 24

progest., estrace

day 25

progest., estrace

day 26

progest., estrace

day 27

progest., estrace

day 28

Blood draw for pregnancy test
progest.
estrace

*progest. = progesterone

Procedure cycle:

Call with menses the month before your scheduled procedure month.

Start Lupron on day 21 of your cycle. Give Lupron between 6:00p.m. and 8:00p.m. Please use barrier contraception this month.

Call when menses restarts while on Lupron. This will occur approximately 10-12 days after starting Lupron. If you have not started your menses after 14 days on Lupron call our office to set up an ultrasound and estradiol appointment.

hMG (Repronex, Menopur) and FSH (Gonal F, Follistim) will be started once suppression has occurred as proven by ultrasound.

Drop Lupron dosage once FSH/hMG have started and continue until day of hCG.

Give FSH/hMG between 6:00p.m. and 8:00p.m.

FSH is given on average for 10-12 days.

hCG (Chorionic Gonadotropin, Pregnyl) 10,000 units is given the day your follicles/eggs are mature. You will be told the specific time you need to take your hCG injection.

Lupron is stopped the day hCG is given.

Oocyte retrieval is done 36 hours after hCG.

Progesterone injection and estrace are begun on day of egg retrieval. Start medrol and tetracycline as directed.

Embryo transfer or ZIFT is done 2 days after egg retrieval.

Pregnancy test 14 days after egg retrieval.

Progesterone and estrace are continued if pregnant.

Lupron Flare or Microdose Lupron Protocol

Procedure month

day 1

menses start,
begin Lupron

day 2

Lupron

day 3

Lupron, FSH, hMG

day 4

Lupron, FSH, hMG

day 5

Lupron, FSH

day 6

Lupron, FSH

day 7

Lupron, FSH

day 8

Lupron, FSH

day 9

Lupron, FSH

day 10

Lupron, FSH

day 11

Lupron, FSH

day 12

hCG trigger shot

day 13

no meds

day 14

Egg Retrieval, progest., estrace

day 15

progest., estrace

day 16

embryo transfer, progest., estrace

day 17

progest., estrace

day 18

progest., estrace

day 19

progest., estrace

day 20

progest., estrace

day 21

progest., estrace

day 22

progest., estrace

day 23

progest., estrace

day 24

progest., estrace

day 25

progest., estrace

day 26

progest., estrace

day 27

progest., estrace

day 28

blood draw for pregnancy test, progest., estrace

*progest. = progesterone

Give FSH between 6:00p.m. and 8:00p.m.

FSH is given on average for 8-11 days.

hMG (Repronex, Menopur) is given for 2 days.

hCG (Chorionic Gonadotropin, Pregnyl) 10,000 units is given the day your follicles/eggs are mature. You will be told the specific time you need to take your hCG injection.

Lupron is stopped after the morning dose on the day hCG is given.

Oocyte retrieval is 36 hours after hCG.

Pprogesterone injection and estrace are begun on day of egg retrieval. Start medrol and tetracycline as directed.

Embryo transfer or ZIFT is done 2 days after egg retrieval.

Pregnancy test 14 days after egg retrieval.

progesterone and estrace are continued if pregnant.

Cetrotide/Ganirelix Protocol

Procedure month

day 1

menses start

day 2

 

day 3

FSH

day 4

FSH

day 5

FSH

day 6

FSH

day 7

FSH

day 8

Cetrotide, FSH, hMG

day 9

Cetrotide, FSH, hMG

day 10

Cetrotide, FSH, hMG

day 11

Cetrotide, FSH, hMG

day 12

Cetrotide, hCG

day 13

 

day 14

Egg Retrieval, progest., estrace

day 15

progest., estrace

day 16

embryo transfer, progest., estrace

day 17

progest., estrace

day 18

progest., estrace

day 19

progest., estrace

day 20

progest., estrace

day 21

progest., estrace

day 22

progest., estrace

day 23

progest., estrace

day 24

progest., estrace

day 25

progest., estrace

day 26

progest., estrace

day 27

progest., estrace

day 28

blood draw for pregnancy test, progest., estrace

*progest. = progesterone

Give FSH between 6:00p.m. and 8:00p.m.

FSH is given on average for 8-11 days.

Cetrotide is started based on the size of the follicles on ultrasound. This is given daily, in the morning, up to and including the day of hCG.

hMG (Repronex, Menopur) is started on the same day as Cetrotide.

hCG (Chorionic Gonadotropin, Pregnyl) 10,000 units is given the day your follicles/eggs are mature. You will be told the specific time you need to take your hCG injection.

Oocyte retrieval is 36 hours after hCG.

Progesterone injection and estrace are begun on day of egg retrieval. Start medrol and tetracycline as directed.

Embryo transfer or ZIFT is done 2 days after egg retrieval.

Pregnancy test 14 days after egg retrieval.

Progesterone and extrace are continued if pregnant.

 

Information from the American Society for Reproductive Medicine under the direction of the Patient Education Committee and the Publications Committee. This information is in no way intended to replace, dictate, or fully define evaluation and treatment by a qualified physician. It is intended solely as an aid for patients seeking general information on issues in reproductive medicine. Copyright 1995 by the American Society for Reproductive Medicine.

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